WHAT DOES PKRRATING MEAN?

The interfacial residues are really conserved among eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements show that the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations aid a product the place activating RNA serves as a scaffold to bind several PKR monomers, growing the regiona

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